‘Banting’ talk by Dr Edith Elliott 19 August, KZN

Aug 11, 2015 No Comments by

Dr Edith Elliott will present a lecture entitled: “Why the Reservations on the ‘Banting’ High Fat Diet?” on Wednesday, 19 August 2015 at 5.45 pm at the John Bews Lecture Theatre, Life Sciences Campus, Carbis Road, Pietermaritzburg.
Abstract: Recent discoveries on the potential effect of diet on cell signalling potentially explain how diet and over-indulgence may lead to type II diabetes, metabolic disease, and potentially cancer, and provide insight into the original and Noakes “Banting Diet”.

The Noakes “High Fat Banting Diet”, like the original “Banting Diet”, results in weight loss largely due to the restriction on dietary sugar or carbohydrates, limiting the intake of sugar-rich drinks and foods, as a sugar/fat addiction has been shown to be a major cause of overindulgence, obesity, type II diabetes and metabolic disease. Though dietary fat is more sustaining than carbohydrate, and the regulation of blood sugar levels is complex, the advocation of an increase in “fat” intake, and a lack of portion control, in the Noakes diet relative to the original Banting Diet, has caused concern.

Habitual consumption of large portions of food, together with a sedentary life style, has been shown to correlate with obesity and the development of metabolic disorders, including type II diabetes. High levels of dietary fat, on the other hand, have been shown to alter sugar metabolism, blocking sugar uptake from the blood until fats are metabolized. This potentially leads to sustained high levels of blood sugar, apparent “insulin insensitivity”, and finally type II diabetes and pathologies associated with diabetes, if the dietary intake of sugars or carbohydrates is not extremely rigorously limited. In people with Founder gene mutations in the receptor for cell uptake of low-density lipoproteins, effects of a high fat diet on cholesterol levels may similarly be serious, potentially inducing metabolic and cardiac disease. The cell biology and signalling basis for such concerns will be explained.

About the Speaker: Edith Elliott obtained a General Pathology Diploma and a Specialist Diploma in Medical Microbiology (University of Rhodesia). She spent 15 years as a Chief Medical Technologist in Government Public Health and Private Pathology Laboratories. A desire for a greater depth of understanding of disease processes led to a BSc and Honours, Masters and PhD degrees in Biochemistry through the University of Natal, Pietermaritzburg. During 25 years as a researcher and Senior Lecturer (UN and UKZN), her research focused on the role of proteolytic enzymes in invasive breast cancer. A secondary focus was the altered cell signalling and movement of enzymes during invasive and metastatic cancer, and in pathogenic mycobacteria, such as TB. Techniques in cell culture, immunoelectron microscopy, laser confocal microscopy and cryoultramicrotomy, were mastered at the European Molecular Biology Laboratory (EMBL) and at Wayne State University’s Department of Pharmacology, Michigan, supported by a Fulbright Scholarship and an EMBL Fellowship. The research resulted in publications in international journals.

All welcome, please support! Light refreshments will be supplied.

Enquiries: Prof. Mike Perrin, Tel. 033 – 260 5118 / 5435.

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